Monovisc® 4 ml 20mg/ml

Monovisc 4 ml 20mg/ml is a single-injection viscosupplement used to treat joint pain caused by osteoarthritis, primarily in the knee. It consists of high molecular weight, cross-linked hyaluronic acid (HA) that mimics the natural fluid found in healthy joints to provide lubrication and cushioning.

Key Product Details
Concentration & Volume: Each pre-filled syringe contains 4 ml of solution with a concentration of 20 mg/ml (or 22 mg/ml depending on the region), delivering a total of roughly 80–88 mg of hyaluronic acid.
Source: It is derived from bacterial fermentation (non-avian source), making it suitable for patients with allergies to bird proteins, such as feathers or eggs.

Use and Administration
Indications: It is indicated for patients with osteoarthritis who have not responded sufficiently to conservative treatments like physical therapy or simple pain relievers like paracetamol (acetaminophen).
Administration: Must be administered as a single intra-articular injection directly into the joint space by a qualified medical professional.
Duration of Effect: A single dose can provide pain relief and improved mobility for up to six months.

Common Side Effects

Most side effects are mild, localized, and typically resolve within a few days.

Injection site reactions: Pain, swelling, redness, or heat at the site.
Joint symptoms: Stiffness, temporary increase in knee pain, or a feeling of “fullness” in the joint.
Systemic reactions: Occasionally, patients may experience headaches, dizziness, or back pain.

Important Precautions

Post-Injection Activity: Patients should avoid strenuous activities (e.g., jogging, tennis, heavy lifting) or prolonged weight-bearing for at least 48 hours following the injection.
Contraindications: Should not be used in patients with known hypersensitivity to hyaluronate products or gram-positive bacterial proteins, or those with infections at the injection site.