Meditoxin® 100u

• Active Ingredient: Clostridium Botulinum Toxin Type A
• Dose: 100 Units/Vial
• Treatment of eye muscle conditions such as strabismus and blepharospasm
• Treatment for severe underarm sweating or hyperhidrosis.
• Help prevent chronic migraines.
• Used for facial wrinkles, square face, face lifting and thin calf, leg lifting

Proper reconstitution of Meditoxin is critical to ensuring both safety and efficacy during treatment. Whether used for cosmetic or therapeutic purposes, the reconstitution process directly affects product performance, stability, and patient outcomes. Errors in preparation can lead to compromised potency, contamination risks, or inaccurate dosing.

To ensure the best results, practitioners should follow these steps meticulously:

Sanitize All Components: Always disinfect vial stoppers, saline ampoules, and syringe hubs with 70% isopropyl alcohol. Let them dry before proceeding to ensure maximum sterilization.
Draw Sterile Saline: Use a 1 mL or 3 mL low dead-space syringe to draw the correct volume of 0.9% sodium chloride, depending on the desired final concentration. Accurate measurement is essential for proper dosing.
Inject Saline Into the Vial: Slowly inject saline down the inside wall of the vial, preventing bubbles or foaming, which could destabilize the neurotoxin proteins.
Mix Gently: Avoid shaking the vial. Instead, tilt and gently swirl the vial or roll it between your palms to dissolve the lyophilized powder. Shaking can damage the toxin’s activity.
Label the Vial: Mark the vial with the date, time, dilution ratio (e.g., 100U/2.5 mL), and your initials. This ensures traceability and proper documentation for safety audits.
Storage: Store reconstituted vials in a medical-grade refrigerator at 2–8°C. The solution remains viable for up to 24 hours. Any unused solution must be discarded to avoid reduced potency and contamination.

Clinical Use Cases
Different facial and body areas respond to botulinum toxin in unique ways, depending on muscle size, movement, and the treatment goals. Meditoxin’s ability to be diluted allows practitioners to tailor the concentration and volume for precise clinical results. Here are some common clinical use cases:

Masseter Muscle (Jaw Slimming or Bruxism)

For treating larger muscles, such as the masseter, which require deeper injections, reconstitute 100 to 200 units with 4–5 mL of saline. This results in a concentration of 20–40 U/mL, ideal for jaw slimming or relieving teeth grinding.
The masseter muscle needs a higher dose for effective treatment and longer-lasting results, typically visible 4–6 weeks after injection.

Platysmal Bands and Neck Rejuvenation

To smooth out vertical neck bands, dilute 100 units in 3 mL of saline to achieve a concentration of about 33 U/mL. This strikes the right balance for targeting the platysma muscle, which is thin and long, ensuring localized action without unintended diffusion into deeper structures like the vocal muscles.