Key Details About Hyalgan®
Manufacturer/Origin: Fidia Farmaceutici S.p.A., Abano Terme, Italy.
Indication: Treatment of knee pain due to osteoarthritis for patients failing to respond to conservative, non-pharmacologic therapies or simple analgesics.
Administration: Intra-articular injection, typically 5 weekly injections, though some patients may benefit from 3.
Composition: 20 mg/2 ml of natural Sodium Hyaluronate (500–730 kDa).
Contraindications: Known hypersensitivity to hyaluronate preparations, allergies to avian proteins/feathers/eggs, or infections at the injection site.
Side Effects: Potential for transient pain, swelling, warmth, or redness at the injection site.
Hyalgan has been studied in over 90 clinical trials. It is widely used for pain relief in early-stage OA, with studies indicating sustained benefits for up to 30 months with repeat treatment cycles.






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