INTRALINE® M4 PLUS Key Features and Benefits
INTRALINE® M4 PLUS is formulated for precise correction of deep wrinkles and contouring needs, delivering durable and natural-looking results.
Deep Wrinkle Treatment: Targets nasolabial folds, marionette lines, and other pronounced wrinkles.
Facial Contouring: Enhances the cheeks, chin, jawline, and performs non-surgical rhinoplasty.
Comfort: Contains 3 mg/mL lidocaine to minimize injection pain.
Long-Lasting Results: Effects last 6–12 months, depending on treatment area and patient factors.
INTRALINE® M4 PLUS Composition
The carefully formulated composition ensures safety, reliability, and effective tissue integration.
Hyaluronic Acid Concentration: 24 mg/mL.
Lidocaine: 3 mg/mL for localized anesthesia.
Cross-Linking Agent: BDDE (<1 μg/mL).
INTRALINE® M4 PLUS Intended Purpose / Indications
This product is designed for deep wrinkle correction, volume restoration, and contour enhancement in facial areas.
Treats deep-set wrinkles, including nasolabial folds and marionette lines.
Provides volume to cheeks, chin, and jawline.
Performs non-surgical rhinoplasty and lip high-definition enhancements.
INTRALINE® M4 PLUS Injection and Treatment Areas
This filler is suitable for targeted treatment of areas requiring volume restoration and definition.
Recommended Areas:
Nasolabial folds, marionette lines.
Cheeks, chin, jawline, and nose.
Lips for high-definition enhancements.
Injection Depth: Subcutaneous or deep dermis.
INTRALINE® M4 PLUS Reconstitution and Preparation Guidelines
INTRALINE® M4 PLUS is pre-filled and ready for immediate use, ensuring ease of application for practitioners.
Preparation Instructions:
Attach the included sterilized 25G or 27G needles securely.
Maintain aseptic conditions throughout preparation and application.
INTRALINE® M4 PLUS Administration and Dosage
Proper administration techniques and dosage are essential to achieving optimal results.
Injection Techniques:
Use linear threading or fan techniques for even distribution.
Massage the area gently after injection to ensure smooth integration.
Dosage:
Typical doses are 1.1 mL per treatment session, tailored to patient needs.
INTRALINE® M4 PLUS Storage Instructions
Storing the product properly ensures its quality and efficacy are maintained.
Store at 2–25°C in a dry, cool place.
Protect from sunlight and freezing conditions.
Ensure the product is used before the expiration date.
INTRALINE® M4 PLUS Contraindications
The product should not be used in certain conditions to prevent complications.
Do Not Use:
In individuals allergic to hyaluronic acid or lidocaine.
On areas with active infections, inflammation, or acne.
During pregnancy or breastfeeding.
In patients under 18 years or with autoimmune diseases.
INTRALINE® M4 PLUS Precautions and Warnings
Following precautions ensures safe and effective application.
Avoid injecting into vascular-rich areas or near permanent fillers.
Do not mix with other injectable products in the same area.
Advise patients on potential risks and ensure thorough consultation.
INTRALINE® M4 PLUS Post-Treatment Care
Patients must follow post-treatment guidelines to achieve the best results and minimize risks.
Aftercare Recommendations:
Avoid makeup for 12 hours post-treatment.
Refrain from UV exposure, extreme heat, or cold for two weeks.
Keep the treated area clean and avoid unnecessary manipulation.
INTRALINE® M4 PLUS Side Effects and Adverse Reactions
Patients should be informed of potential side effects, which are typically mild and temporary.
Common Side Effects:
Redness, swelling, and tenderness at the injection site.
Minor lumps or discoloration.
Severe Reactions:
Rare occurrences of granulomas or vascular occlusion.
Immediate medical attention required for severe or persistent symptoms.






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