KARISMA RH COLLAGEN SOFTFILLER BIORESTITUTIVO FACE is an innovative bio-restitutive soft filler designed to promote the natural restoration of pre-aging skin conditions. By stimulating the production of type I collagen in fibroblasts, it enhances skin firmness and elasticity. This advanced filler is classified as an injectable MD Class III medical device, offering a safe and effective solution for skin rejuvenation. With its unique composition, it provides long-lasting hydration and structural support, ensuring visible improvement in skin texture and elasticity over time.
R polypeptides α1 chain of type I collagen (produced by transgenic silkworm technology)
High Molecular Weight Hyaluronic Acid
Carboxymethyl Cellulose (CMC)
KARISMA RH COLLAGEN SOFTFILLER BIORESTITUTIVO FACE Key Features and Benefits
This soft filler is formulated to provide multi-faceted benefits that go beyond simple volume restoration. It works by deeply hydrating the skin, enhancing collagen production, and preventing the degradation of existing collagen fibers. Clinical studies have demonstrated its effectiveness in improving skin texture, reducing wrinkles, and restoring a youthful appearance. Unlike traditional fillers, KARISMA RH COLLAGEN SOFTFILLER BIORESTITUTIVO FACE supports long-term skin regeneration and hydration, making it an optimal choice for aesthetic and dermatological applications.
Stimulates collagen production, enhancing skin firmness and elasticity.
Long-lasting hydration due to high molecular weight hyaluronic acid.
Non-immunogenic recombinant collagen minimizes allergic reactions.
Prevents collagen degradation by inhibiting hyaluronidase and MMPs (Matrix Metalloproteinases).
Clinically proven improvement in skin texture and structure.
Safe and effective, with a low incidence of side effects.
KARISMA RH COLLAGEN SOFTFILLER BIORESTITUTIVO FACE Composition
Understanding the composition of KARISMA RH COLLAGEN SOFTFILLER BIORESTITUTIVO FACE is essential in appreciating its regenerative and anti-aging effects. This advanced filler is designed with a balanced combination of high molecular weight hyaluronic acid, recombinant collagen, and carboxymethyl cellulose. Each of these components plays a vital role in promoting skin regeneration, hydration, and overall skin health. The synergy between these ingredients ensures optimal biocompatibility and long-lasting results for patients seeking a natural approach to skin rejuvenation.
200 mg/mL High Molecular Weight Hyaluronic Acid
200 µg/mL Recombinant Polypeptide of Collagen-1 Alpha Chain
40 mg/mL Carboxymethyl Cellulose (CMC)
KARISMA RH COLLAGEN SOFTFILLER BIORESTITUTIVO FACE Intended Purpose / Indications
The primary purpose of KARISMA RH COLLAGEN SOFTFILLER BIORESTITUTIVO FACE is to restore skin elasticity, hydration, and volume while reducing the visible signs of aging. It is specifically formulated to address facial wrinkles, improve skin structure, and provide a youthful appearance without causing adverse immune reactions. This filler is ideal for patients seeking non-surgical solutions for facial contouring, wrinkle reduction, and treatment of acne scars. With its advanced formulation, it provides a natural and long-lasting rejuvenation effect.
Designed for:
Wrinkle reduction (fine lines, deep wrinkles, and folds)
Facial contouring (cheeks, chin, and jawline)
Volume restoration in atrophic areas
Improvement of skin texture and hydration
Treatment of acne scars and aging-related skin concerns
KARISMA RH COLLAGEN SOFTFILLER BIORESTITUTIVO FACE Side Effects and Adverse Reactions
Like any aesthetic treatment, KARISMA RH COLLAGEN SOFTFILLER BIORESTITUTIVO FACE may cause mild to moderate side effects. Most reactions are temporary and subside within a few days, but patients should be informed about possible risks before undergoing treatment. Severe reactions are rare, but if they occur, medical attention should be sought immediately.
Common and mild reactions:
Redness, swelling, bruising (resolved within a few days)
Mild discomfort at the injection site
Severe reactions (rare):
Allergic responses
Intravascular injection leading to embolism (extremely rare but serious)






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